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Figure 1 | Orphanet Journal of Rare Diseases

Figure 1

From: Stilbenes and resveratrol metabolites improve mitochondrial fatty acid oxidation defects in human fibroblasts

Figure 1

Effects of 75 μM resveratrol for 48 h on ß-oxidation in fibroblasts from control, CPT2-, or VCAD-deficient patients. A) Quantification of palmitate oxidation flux. The results are means ± SEM of at least three different experiments. In each experiment, the determinations were performed in triplicate. Control values are from three different healthy individuals. ***P < 0.001 compared with vehicle-treated fibroblasts. B) Quantification of C16:0 acylcarnitine production by tandem mass spectrometry. Results are expressed relative to cell proteins and are means ± SEM. ***P < 0.001, when compared with vehicle-treated cells, $$$ P < 0.001 compared with control fibroblasts.

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