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Figure 2 | Orphanet Journal of Rare Diseases

Figure 2

From: Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G93A ALS mice: overlapping effects or limited therapeutic opportunity?

Figure 2

PRE + RSV treatment preserves lower motoneuron function. Electrophysiological tests performed in (A) female and (B) male SOD1G93A mice revealed significant preservation of compound muscle action potentials (CMAP) amplitude in treated groups. Values are mean ± SEM. *p < 0.05, **p < 0.01 PRE-084 vs. untreated; α p < 0.05, αα p < 0.01 PRE + RSV vs. untreated; ββ p < 0.01 RSV vs. untreated.

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