Skip to main content
Figure 5 | Orphanet Journal of Rare Diseases

Figure 5

From: Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticum

Figure 5

Relative expression of mediators in MSX2-Wnt signalling (MSX2, DLX5, LEF-1, TCF-1 and β-catenin). qPCR reveals a marked upregulation of MSX2, LEF-1 and TCF-1 as well as significant downregulation of DLX5 in human PXE fibroblasts compared to control cells. β-catenin is not differentially expressed in PXE fibroblasts. (n = 8 and 5 for patients and controls respectively). *p < 0.05.

Back to article page

Orphanet Journal of Rare Diseases

ISSN: 1750-1172