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Table 5 Country-specific multiple linear regression models after stepwise reduction

From: Shining a light in the black box of orphan drug pricing

 

Belgium R2 = 0.739 n = 51 Constant = 4.734

France R2 = 0.716 n = 59 Constant = 4.911

Netherlands R2 = 0.570 n = 52 Constant = 4.170

Czech republic R2 = 0.706 n = 41 Constant = 4.329

Italy R2 = 0.656 n = 28 Constant = 5.098

United Kingdom R2 = 0.661 n = 66 Constant = 4.652

Variable (x)

Unstand. coeff.

p-value

Unstand. coeff.

p-value

Unstand. coeff.

p-value

Unstand. coeff.

p-value

Unstand. coeff.

p-value

Unstand. coeff.

p-value

MultipleIND

  

0.504

0.001

0.570

0.010

    

0.312

0.028

Repurposed

−0.573

0.006

−0.548

0.002

−0.557

0.005

−0.656

0.006

  

−0.325

0.039

altTx

−0.478

0.026

−0.584

0.001

    

−0.988

0.000

−0.397

0.011

Oral

−0.637

0.000

−0.328

0.023

  

−0.678

0.001

  

−0.392

0.006

Survimp

      

0.443

0.035

    

Chronic

0.464

0.025

    

0.445

0.044

  

0.296

0.089

ImprovQoL

0.565

0.021

    

0.509

0.060

    
  1. Explanatory variables are described in Table 2. N denotes the number of observations. Unstand. coeff. = unstandardized coefficients.