From: Shining a light in the black box of orphan drug pricing
Belgium R2 = 0.739 n = 51 Constant = 4.734 | France R2 = 0.716 n = 59 Constant = 4.911 | Netherlands R2 = 0.570 n = 52 Constant = 4.170 | Czech republic R2 = 0.706 n = 41 Constant = 4.329 | Italy R2 = 0.656 n = 28 Constant = 5.098 | United Kingdom R2 = 0.661 n = 66 Constant = 4.652 | |||||||
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Variable (x) | Unstand. coeff. | p-value | Unstand. coeff. | p-value | Unstand. coeff. | p-value | Unstand. coeff. | p-value | Unstand. coeff. | p-value | Unstand. coeff. | p-value |
MultipleIND | 0.504 | 0.001 | 0.570 | 0.010 | 0.312 | 0.028 | ||||||
Repurposed | −0.573 | 0.006 | −0.548 | 0.002 | −0.557 | 0.005 | −0.656 | 0.006 | −0.325 | 0.039 | ||
altTx | −0.478 | 0.026 | −0.584 | 0.001 | −0.988 | 0.000 | −0.397 | 0.011 | ||||
Oral | −0.637 | 0.000 | −0.328 | 0.023 | −0.678 | 0.001 | −0.392 | 0.006 | ||||
Survimp | 0.443 | 0.035 | ||||||||||
Chronic | 0.464 | 0.025 | 0.445 | 0.044 | 0.296 | 0.089 | ||||||
ImprovQoL | 0.565 | 0.021 | 0.509 | 0.060 |