Table 6 Multiple regression analysis on factors associated with HRQoL in patients with TTR mutations
Predictor variable | Parameter estimate | Standard error | t value | p value |
|---|---|---|---|---|
Intercept | 0.99 | 0.03 | 30.53 | <0.001 |
Gender (male vs. female) | 0.00 | 0.01 | -0.11 | 0.909 |
Age at onset (early vs. late) | -0.09 | 0.01 | -6.19 | <0.001 |
Disease duration (years) | -0.01 | 0.00 | -6.90 | <0.001 |
Upper GI symptoms | -0.07 | 0.01 | -4.77 | <0.001 |
Lower GI symptoms | -0.13 | 0.01 | -9.28 | <0.001 |
LTx at enrollment | 0.06 | 0.02 | 3.19 | 0.002 |