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Table 5 Multiple regression analysis on factors associated with the nutritional status in patients with TTR mutations

From: THAOS: Gastrointestinal manifestations of transthyretin amyloidosis - common complications of a rare disease

Predictor variable Parameter estimate Standard error t value p value
Intercept 1214.40 43.12 28.16 <0.001
Gender (male vs. female) -11.13 17.39 -0.64 0.522
Age at onset (early vs. late) -34.48 18.96 -1.82 0.069
Disease duration (years) -3.80 1.34 -2.83 0.005
Upper GI symptoms -81.42 19.96 -4.08 <0.001
Lower GI symptoms -98.40 18.91 -5.20 <0.001
LTx at enrollment -48.53 25.98 -1.87 0.062
  1. The modified body mass index (mBMI), in which BMI was multiplied with serum albumin, was used to assess the nutritional status. Age of onset <50 years was regarded as early-onset. GI: gastrointestinal; LTx: liver transplant.