Table 2 Distribution of GI symptoms in patients with ATTR amyloidosis
Symptom | Wild-type | TTR mutation |
|---|---|---|
n = 140 | n = 1114 | |
Any GI symptom | 21 (15.3%) | 696 (63.0%) |
Early satiety | 5 (3.6%) | 291 (26.4%) |
Nausea | 3 (2.2%) | 189 (17.1%) |
Vomiting | 0 (0.0%) | 147 (13.4%) |
Constipation | 5 (3.6%) | 230 (20.9%) |
Diarrhea/constipation | 2 (1.5%) | 267 (24.3%) |
Diarrhea | 5 (3.6%) | 218 (19.8%) |
Fecal incontinence | 0 (0.0%) | 68 (6.2%) |
Unintentional weight loss | 4 (2.9%) | 346 (31.5%) |