Skip to main content

Table 2 Distribution of GI symptoms in patients with ATTR amyloidosis

From: THAOS: Gastrointestinal manifestations of transthyretin amyloidosis - common complications of a rare disease

Symptom Wild-type TTR mutation
n = 140 n = 1114
Any GI symptom 21 (15.3%) 696 (63.0%)
Early satiety 5 (3.6%) 291 (26.4%)
Nausea 3 (2.2%) 189 (17.1%)
Vomiting 0 (0.0%) 147 (13.4%)
Constipation 5 (3.6%) 230 (20.9%)
Diarrhea/constipation 2 (1.5%) 267 (24.3%)
Diarrhea 5 (3.6%) 218 (19.8%)
Fecal incontinence 0 (0.0%) 68 (6.2%)
Unintentional weight loss 4 (2.9%) 346 (31.5%)
  1. Number of patients, n (%), reporting gastrointestinal (GI) symptoms at enrollment.