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Table 3 Somatosensory evoked responses according to the presence or absence of symptoms of 25 ×-ALD heterozygote women

From: Neurological impairment among heterozygote women for X-linked Adrenoleukodystrophy: a case control study on a clinical, neurophysiological and biochemical characteristics

Somatosensory evoked responses

All 25 heterozygote females

Presence of symptoms

p

Symptomatic women: 23

Asymtomatic women: 2

Upper Limbs (N20, or somatosensory cortex contralateral to the wrist stimulated) in ms

Mean ± sd

19.2 ± 1.1

20.1 ± 4.2

18 ± 0.9

ns *

Above the cutoff value of 20.5 ms

6/25

6/23

0/2

ns #

Lower Limbs (P40, or somatosensory cortex ipsilateral to the tibial nerve stimulated) in ms

Mean ± sd

38 ± 2,5

55.3 ± 32.8

38.9 ± 3.8

ns *

Above the cutoff value of 41,5 ms

18/25

17/23

1/2

ns #

  1. * Mann-Whitney U; m/s = meters per second; mV – milivolts; μV = microvolts.