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Figure 2 | Orphanet Journal of Rare Diseases

Figure 2

From: EPS8, encoding an actin-binding protein of cochlear hair cell stereocilia, is a new causal gene for autosomal recessive profound deafness

Figure 2

Immunolocalization of EPS8 in the mouse cochlea and macaque retina. (A-C) Immunolabeling for F-actin (A) and EPS8 (B) in the mouse cochlea. DAPI (D) was used to label cell nuclei. Immunolabeling of EPS8 (E and H), synaptophysin (F) and whirlin (I) in the macaque retina. A polyclonal antibody was used to detect EPS8. (G) Co-immunolabeling of EPS8 and synaptophysin (J) Co-immunolabeling of EPS8 and whirlin. Abbreviations: OS, outer segment; ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer; IPL, inner plexiform layer; GNL, ganglion nuclear layer. Scale bars: 5 μm.

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