Table 8 *Incremental costs per quality adjusted life year gained under different scenarios, undiscounted (upper rows) and discounted (lower rows)
From: Cost-effectiveness of enzyme replacement therapy for type 1 Gaucher disease
Scenario | QALY | Costs | ICER | ||||
|---|---|---|---|---|---|---|---|
ERT | no ERT | Δ | ERT | no ERT | Δ | ||
Base case | 62.13 | 55.86 | 6.27 | €5,716,473 | €171,780 | €5,544,693 | €884,994 |
37.33 | 34.65 | 2.67 | €1,206,933 | €50,048 | €1,156,885 | €432,540 | |
Production loss included | 62.13 | 55.86 | 6.27 | €5,772,897 | €294,226 | €5,478,670 | €874,456 |
37.33 | 34.65 | 2.67 | €1,216,954 | €71,956 | €1,144,998 | €428,096 | |
25% ERT costs reduction | 62.13 | 55.86 | 6.27 | €4,338,430 | €171,780 | €4,166,649 | €665,043 |
37.33 | 34.65 | 2.67 | €918,801 | €50,048 | €868,753 | €324,812 | |
Historical I | 33.00 | 28.50 | 4.50 | €5,202,872 | €109,342 | €5,093,530 | €1,131,036 |
24.27 | 21.35 | 2.92 | €2,391,020 | €54,143 | €2,336,877 | €800,359 | |
Historical II | 30.28 | 24.65 | 5.64 | €6,198,258 | €112,774 | €6,085,484 | €1,079,504 |
22.52 | 18.78 | 3.74 | €3,031,062 | €59,253 | €2,971,809 | €794,656 | |