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Table 4 Mean ICARS Kinetic Functions Subscale Score by Visit (ITT Population)

From: Intra-Erythrocyte Infusion of Dexamethasone Reduces Neurological Symptoms in Ataxia Teleangiectasia Patients: Results of a Phase 2 Trial

 

Mean (SD)

95% CI for the mean

MeanΔ (SD)

95% CI for meanΔ

Median

Min-max

p-value*

V1

23.1 (6.2)

(20.5/25.7)

-

 

23.5

2–36

-

V2

22.0 (5.0)

(19.9/24.1)

-1.1 (3.3)

(-2.5/0.3)

22.0

6–32

-

V4

20.6 (5.2)

(19/22.6)

-2.5 (4.7)

(-4.6/-0.6)

21.0

6–28

0.027

V7

20.2 (5.1)

(18.1/22.3)

-2.9 (3.8)

(-4.5/-1.3)

20.5

6–28

0.003

  1. *Comparison vs. baseline (V1) using Wilcoxon non-parametric test.