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Table 1 Mean ICARS Total Score and Changes from Baseline (V1) by Visit (ITT Population)

From: Intra-Erythrocyte Infusion of Dexamethasone Reduces Neurological Symptoms in Ataxia Teleangiectasia Patients: Results of a Phase 2 Trial

  ICARS total score 95% CI for the mean MeanΔ (SD) 95% CI for meanΔ Median Min-max p-value*
V1 50.6 (12.8) (45.2/56) -   52.5 8–72 -
V2 48.4 (11.4) (43.6/53.2) -2.2 (5.6) (-4.6/0.2) 48.5 14–68 0.107
V4 47.4 (11.5) (44/51.8) -3.4 (7.3) (-6.7/0.1) 49.0 14–62 0.054
V7 46.6 (12.3) (41.4/51.8) -4.0 (7.5) (-7.1/-0.9) 48.0 14–62 0.024
  1. *Comparison vs. baseline (V1) using Wilcoxon non-parametric test.