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Table 6 Concurrent malignancies in 93 South Florida patients with GD1

From: Patients with type 1 Gaucher disease in South Florida, USA: demographics, genotypes, disease severity and treatment outcomes

    Malignancy No of patients   Ages at CA Dx (y) Mean age at CA Dx (y)
Monoclonal gammopathy 4 54, 68, 70#, 82# 68.5
Cutaneous Squamous CA 5 59, 66, 66, 77, 80 69.6
Myelodysplasia, AML 3 51*, 63*, 72* 62.0
Non-Hodgkin’s lymphoma 3 59, 74*, 83 72.0
Breast carcinoma 3 47#, 72#, 75 64.7
Cutaneous Melanoma 2 57, 71 64.0
Prostate carcinoma 2 65, 75 70.0
Bladder carcinoma 1 80 80.0
Lung cancer 1 62* 62.0
Fallopian tube carcinoma 1 49§# 49.0
Cervical carcinoma in situ 1 53 53.0
  1. *Cause of death.
  2. §BRCA2 mutation.
  3. #Never treated with ERT or SSIT.