Table 4 Literature review of studies that have addressed ethnycity related differences according to phenotype and outcome of BD [7, 8, 10, 11, 13–16]
From: Ethnicity and association with disease manifestations and mortality in Behçet’s disease
First author | Country | Year of publication | Nb of patients | Ethnicity | Observations* |
|---|---|---|---|---|---|
Wechsler | Paris (France) | 1988 | 196 | French Men (n = 36) and North African men (n = 160). | No significant difference |
Zouboulis | Allemangne | 1997 | 196 | Allemands (n = 82), Immigrés Turques (n = 86) patients originaires de pays étrangers autres (n = 28) | Plus d’atteintes oculaires chez les patients du Sud-Est de l'Europe (Italie, Gèce) et de Turquie. 25% des patients avec évolution défavorable, 3 décès, tous Allemands. |
Zouboulis | Germany | 1997 | 196 | German (n = 82), Turkish immigrants (n = 86), and patients from other foreign countries (n = 28) | Ocular disease is more frequent in South-Eastern European patients and in Turkish immigrants. |
Muhaya | Kurume (Japan) London (England) | 2000 | 54 | Japanese (n = 35) and British (n = 19) (including: 12 caucasians, 5 Middle Eastern, 1 African, 1 Asian) | Kurume patients have more active anterior uveitis and more posterior uveitis than London patients. |
Krause | Tel Aviv (Israel) | 2001 | 100 | Jewish patients (n = 66) (most of them originated from Iran/Iraq, Turkey and North African countries) and Arabic patients (n = 34) | Arabic patients have more severe ocular diseases. Jewish patients from North African countries have higher disease severity score. |
Kotter | Tübingen (Germany) | 2004 | 65 | German (n = 32) and Turkish descents (n = 33) | No significant difference |
Rozenbaum | Northern area of Israel | 2007 | 53 | Arabs (n = 30) and Druzes (n = 23) | Higher frequency of uveitis, of deep vein thrombosis, and of CNS involvement, and a higher global severity score in Arabs. |
Mahr | Seine-Saint-Denis County (France) | 2008 | 79 | European patients (n = 19) and non-European patients (n = 60). | No significant difference |
Mohammad | Skåne (Sweden) | 2012 | 40 | Swedish ancestry (n = 12) and non-Swedish ancestry (28/40, 70%) [Middle East (n = 15), Africa (n = 2), East Asia (n = 2); Turkey (n = 2), Central and Eastern Europe (n = 6)] | No significant difference |