Table 2 Basal clinical and laboratory features of patients initially treated with D-penicillamine or zinc
D-Penicillamine | Zinc | P values | |
|---|---|---|---|
Patients (N) | 27 (21 males) | 15 (9 males) | |
Median age at diagnosis (months) | 75 (range 39–192) | 42 (range 12–101) | <0.001* |
Median ALT at diagnosis (UI/L) | 251 (range 23–582) | 110 (range 12–502) | 0.022* |
Median AST at diagnosis (UI/L) | 114 (range 27–205) | 67 (range 22–168) | 0.059 (NS) |
Median GGT at diagnosis (UI/L) | 72 (range 11–267) | 21 (range 13–119) | 0.019* |
Basal urinary copper (μg/24 h) | 150 (range 14–413) | 31 (range 4–780) | 0.91 (NS) |
Median liver copper content (μg/g dry tissue) | 780 (range 60–1660) | 989 (range 407–1230) | 0.423 (NS) |