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Table 2 ICEP patient characteristics at diagnosis

From: Idiopathic eosinophilic pneumonia in children: the French experience

Patient Clinical presentation Biology Imagery Spirometry
Sex Age at diagnosis (years) Atopic history Delay to diagnosis (days) Respiratory symptoms Respiratory exam General symptoms Initial blood Eo count/mm3 Maximal blood Eo count/mm3 Total IgE kU/L Lymphocyte phenotype T-cell clonality ANA BALF cellularity (cell/mm3) BALF Eo % BALF lymphocytes % BALF neutrophils % BALF macrophages % Histology CT scan  
1 F 15.5 No 60 ED, RD, DC, T DBS yes 1510 4600 799 normal No 1/1280 160,000 28 17 2 53 nd AO, GGO, N, IST, Ad, B, PE R, O, D
2 F 13.9 No 60 ED, RD, DC W, DBS yes 4601 4600 165 normal No _ 390,000 44 6 4 46 nd AO, GGO, B, BV, Ad R, O, D
3 F 6.8 Yes 120 ED, PC normal no 1100 1100 >5000 normal No 1/100 241,000 21 20 5 52 Positive dGGO, RN R
4 M 5 Yes 90 DC W no 33,580 48,920 150 2,2% CD3+ CD4- CD8- with TCR αβ nd _ 450,000 20 5 2 73 nd pGGO, N, Ad R
5 F 11.2 Yes 37 ED, RD, DC, CP H, P yes 80 1300 1040 nd Positive (TCR γ gene) nd 112,000 14 16 43 27 nd dGGO, RN, Ad, PM nd
  1. Footnote: F: female, M: male, nd: not determined, ED: exertional dyspnea, RD: rest dyspnea, DC: dry cough, T: chest tightness, PC: productive cough, CP: chest pain, DBS: decreased breath sound, W: wheezing, H: hypoxemia ,P: polypnea, Eo: eosinophils, ANA: antinuclear antibodies, BALF: broncho-alveolar lavage fluid, AO: alveolar opacities, GGO: ground-glass opacities, N: nodules, IST: interlobular septal thickening, Ad: adenopathy, B: bronchiectasis, PE: pleural effusions, BV: peri-broncho-vascular thickening, RN: reticulonodular syndrome, N, nodules, PM: pneumomediastinum, d: diffuse, p: patchy, , D: diffusion impairment, R: restriction, O: obstruction, in bold: diagnostic criteria.