From: Idiopathic eosinophilic pneumonia in children: the French experience
Inclusion criteria for ICEP based on adults series3 | Inclusion criteria for IAEP based on adults series3 |
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1) respiratory symptoms present> 2 weeks | 1) acute onset with febrile respiratory symptoms (< 1 month, and especially < 7 days duration before medical examination) |
2) diffuse pulmonary alveolar consolidation with air bronchogram and/or ground-glass opacities at chest imaging, especially with peripheral predominance | |
2) bilateral diffuse infiltrates on imaging | |
3) eosinophil count in bronchoalveolar lavage fluid (BALF) > 40% and/or peripheral blood eosinophilia > 1x109cells/L | 3) PaO2 in room air < 60 mmHg, or PaO2/FiO2 < 300 mmHg, or oxygen saturation (SpO2) in room air < 90% |
4) absence of other known causes of eosinopilic lung disease* | 4) lung eosinophilia with > 25% eosinophils in BALF |
5) absence of determined cause of acute eosinophilic pneumonia* (including infection or drug exposure) - recent onset of tobacco smoking or exposure to inhaled dusts may be present |