Figure 2From: The supposed tumor suppressor gene WWOX is mutated in an early lethal microcephaly syndrome with epilepsy, growth retardation and retinal degenerationBrain MRIs of II:4. A Supratentorial atrophy with thin cerebral cortex (yellow arrow) and hippocampal dysplasia (red arrow) are visible in the coronal plane. B Hypoplasia of corpus callosum. Note craniofacial dysproportion and sloping forehead (sagittal MRI). C Hypotrophic temporal lobes with widened subarachnoidal space (blue arrow), hippocampal malformation (red arrow) and gyral pattern anomaly (axial MRI).Back to article page