Advertisement
Table 3 Management program for men and woman with CS from the National Comprehensive Cancer Network[30]
| Woman | |
|---|---|
| • | Breast awareness starting at age 18 y |
| • | Clinical breast exam, every 6–12 month, starting at age 25 y or 5–10 y before the earliest known breast cancer in the family |
| • | Annual mammography and breast MRI screening starting at age 30–35 y or individualized based on earliest age of onset in family |
| • | For endometrial cancer screening, encourage patient education and prompt response to symptoms and participation in a clinical trial to determine the effectiveness or necessity of screening modalities |
| • | Discuss risk-reducing mastectomy and hysterectomy and counsel regarding degree of protection, extent of cancer risk and reconstruction options |
| • | Address psychosocial, social, and quality-of-life aspects of undergoing risk-reducing mastectomy and/or hysterectomy |
| Men and Woman | |
| • | Annual comprehensive physical exam starting at age 18 y or 5 y before the youngest age of diagnosis of a component cancer in the family (whichever comes first), with particular attention to breast and thyroid exam |
| • | Annual thyroid starting at age 18 y or 5-10 y before the earliest known thyroid cancer in the family, whichever is earlier |
| • | Colonoscopy, starting at age 35 y, then every 5 y or more frequently if patient is symptomatic or polyps found |
| • | Consider renal ultrasound starting at age 40 y, then every 1-2 y |
| • | Dermatological management may be indicated for some patients |
| • | Consider psychomotor assessment in children at diagnosis and brain MRI if there are symptoms |
| • | Education regarding the signs and symptoms of cancer |
