Figure 4From: An algorithm to predict phenotypic severity in mucopolysaccharidosis type I in the first month of lifeAlgorithm for assessment of phenotypic severity in MPS I patients. Mutational analysis, residual IDUA activity and clinical characteristics present before the age of 1 month are combined. 1Measured as described in this article. 2Upper airway obstruction included the following symptoms: excessive snoring during sleep, continuously runny nose, obstructive sleep apneas, feeding difficulties due to obstructed nasal breathing.Back to article page