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Table 2 Updated risk level of drugs and toxins known to be associated with PAH

From: Pulmonary arterial hypertension

1. Definite  
  Aminorex
  Fenfluramine
  Dexfenfluramine
  Toxic rapeseed oil
  Benfluorex
2. Likely  
  Amphetamines
  L-tryptophan
  Metamphetamines
  Dasatinib
3. Possible  
  Cocaine
Phenylpropanolamine
St John’s Wort
  Chemotherapeutic agents
  Selective serotonin reuptake inhibitors
  Pergolide
4. Unlikely  
  Oral contraceptives
  Estrogen therapy
  Cigarette smoking
  1. *This table was adapted from Galiè et al. [15].