Figure 1

Clinical features in 44 patients with SURF1 deficiency. The x axis indicates the age of onset (years) and the y axis indicates the clinical features. Percentages denote the proportion of patients with a given clinical feature, and box-and-whisker plots show the age of onset. The median age of onset is indicated by the vertical line within the boxes. Boxes represent upper and lower quartiles, whiskers represent extreme values, and dots represent outliers which are ≥1.5 times the interquartile range from the median. Other less commonly observed features included hypertrichosis (41%), optic atrophy (23%), encephalopathy (20%), seizures (14%) and cardiomyopathy (2%).