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Table 5 Relative proportion of B cell subsets in the Olmsted syndrome case and age-matched healthy controls

From: Olmsted syndrome: exploration of the immunological phenotype

Subset

Definition

Patient (%)

Healthy volunteers (%)

 
   

Mean (SD)

Median (min-max)

B cells

CD19+

25.7

28.9 (11.5)

26.5 (16.9-55.1)

 →Naïve

IgM+CD27-

84.5

76.9 (4.51)

76.9 (68.9-84.7)

 →Memory

IgM+CD27+

1.91

2.84 (1.00)

2.58 (1.61-4.65)

 →Switched memory

IgM-CD27+

4.40

7.30 (2.15)

6.82 (4.3-12.0)

 →IgE+

IgE+

0.09

0.13 (0.09)

0.11 (0.04-0.37)

 →Transitional

CD24hiCD38hi

12.0

4.94 (2.10)

4.63 (1.76-8.14)

  1. CD19+ B cells are shown as percentage of total lymphocytes; all other B cell subsets are shown as percentage of CD19+ B cells.