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Table 4 T lymphocyte profile of Olmsted syndrome case and age-matched healthy controls

From: Olmsted syndrome: exploration of the immunological phenotype

Subset Defining surface markers Patient (%) Healthy volunteers (%)  
    Mean (SD) Median (min-max)
T cells CD3+ 25.0 21.7 (10.7) 20.2 (8.48-41.6)
CD4 + subsets     
CD4+ T cells CD4+CD8- 18.2 11.0 (6.03) 7.79 (3.82-19.9)
 →Treg Foxp3+ 1.91 3.67 (2.52) 2.97 (1.54-9.37)
 →Th1 IFNγ+ 1.22 3.18 (1.57) 3.36 (0.96-5.28)
 →Th2 IL-4+ 2.14 5.03 (2.45) 5.12 (1.90-11.0)
 →Th17 IL-17+ 0.08 0.05 (0.04) 0.03 (0–0.1)
 →IL-2+ IL-2+ 1.69 2.25 (1.06) 2.67 (0.95-4.11)
 →Tfh CD45RA-CXCR5+ 0.59 0.14 (0.11) 0.11 (0.026-0.41)
 →Naïve CD45RA+CCR7+ 61.3 44.1 (9.73) 43.6 (31.0-58.4)
 →RTE CD45RA+CCR7+CD31+ 46.3 35.6 (8.77) 35.7 (22.8-49.7)
 →TCM CD45RA-CCR7+ 14.6 12.2 (4.24) 11.6 (6.36-18.7)
 →TEM CD45RA-CCR7- 15.6 32.5 (7.54) 35.2 (21.0-43.7)
 →TEMRA CD45RA+CCR7- 8.50 11.9 (5.55) 7.78 (6.52-21.2)
CD8 + subsets     
CD8+ T cells CD4-CD8+ 7.75 9.51 (4.12) 8.64 (4.45-17.5)
 →IFNγ+ IFNγ+ 8.1 23.3 (9.09) 19.9 (12.7-40.0)
 →IL-2+ IL-2+ 1.48 3.46 (1.74) 2.82 (1.78-7.17)
 →Naïve CD45RA+CCR7+ 60.9 41.2 (13.9) 37.4 (26.3-62.2)
 →RTE CD45RA+CCR7+CD31+ 59.0 38.2 (14.0) 32.3 (24.0-60.0)
 →TCM CD45RA-CCR7+ 3.08 3.11 (1.52) 2.91 (1.08-6.00)
 →TEM CD45RA-CCR7- 16.0 24.1 (7.63) 22.0 (14.8-41.3)
 →TEMRA CD45RA+CCR7- 20.1 31.6 (12.5) 31.2 (15.3-49.9)
  1. The frequency of CD3+ cells is shown as percentage from all leukocytes. CD4+ subsets and CD8+ subsets are from percentage CD4+ and CD8+ respectively.