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Table 3 Frequency of major leukocyte subsets from patient with mutation in TRPV3 and age-matched healthy controls

From: Olmsted syndrome: exploration of the immunological phenotype

Subset Defining surface markers Patient (%) Healthy volunteers (%)  
    Mean (SD) Median (min-max)
T cells CD3+ 25.0 21.7 (10.7) 20.2 (8.48-41.6)
B cells CD19+ 25.7 28.9 (11.5) 26.5 (16.9-55.1)
γδ T cells γδ TCR+ 0.25 0.23 (0.21) 0.15 (0.04-0.72)
iNKT cells CD3+Vα24Jα18+ 0.49 0.52 (0.25) 0.55 (0.09-0.89)
NKT cells CD3+CD56+ 2.49 10.2 (4.91) 9.35 (4.15-16.8)
NK cells CD3-CD19-CD14-CD11c-CD56+ 22.0 21.2 (10.1) 18.2 (9.17-40.8
Dendritic cells CD3-CD19-CD14-CD56- 6.67 6.66 (2.76) 6.21 (2.96-11.4)
 →mDC CD11c+HLA-DR+ 35.5 41.4 (6.17) 42.2 (31.8-55.4)
 →pDC CD11c-CD123+ 21.3 16.8 (10.9) 19.9 (3.88-39.25)
  1. T cells are shown as percentage total leukocytes; B cells and γδ T cells are shown as percentage total lymphocytes; iNKT and NKT cells as percentage T cells; NK cells and dendritic cells are shown as percentage total leukocytes while mDC and pDC are shown as percentage dendritic cells.