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Table 1 Comparison of selected clinical features in WS vs non-WS patients with 3q deletions

From: Dandy-Walker malformation and Wisconsin syndrome: novel cases add further insight into the genotype-phenotype correlations of 3q23q25 deletions

  WS (n = 12)* Non-WS (n = 15)*
Core gestaltic features
Coarse facies 12 (100%) 0
Prominent or wide triangular shaped nasal tip 12 (100%) 3 (20%)
High arched or upsweeping eyebrows 11 (92%) 0
Full/everted lower lip 11 (92%) 5 (33%)
Bushy eyebrows 10 (83%) 3 (20%)
Other recurrent clinical features
Developmental delay/intellectual disability 12 (100%) 15 (100%)
Digital anomalies: 10 (83%) 6 (40%)
 -of which short IV metatarsus 4 (33%) 0
Ear anomalies 9 (75%) 13 (87%)
Macrostomia 8 (67%) 1 (7%)
Smooth/simplified philtrum 7 (58%) 7 (47%)
  1. *Identification codes, detailed clinical features, cytogenetic characterization and references for patients with and without WS are given in Additional file 1: Table S1.