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Table 7 Diagnostic recommendations in pLCH

From: Management of adult patients with Langerhans cell histiocytosis: recommendations from an expert panel on behalf of Euro-Histio-Net

Recommendation Grade
Confirm definitive diagnosis  
• in all patients before start of systemic therapy D2
• prefer lung biopsy D2
• HRCT is required in all patients D2
Exclude Existence Of Multi System LCH D2