Recommendation | Grade |
---|---|
Isolated “Unresectable” lesion: | C2 |
if a resection would significantly compromise anatomic function, e.g. odontoid peg, CNS | |
Recurrent or progressive lesion: | C2 |
In multifocal or multisystem disease only in case of minor response to standard systemic therapy | |
Adjuvant treatment following marginal or incomplete resection: especially in single system bone disease with soft tissue involvement | C2 |