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Table 3 Baseline laboratory and radiographic evaluation

From: Management of adult patients with Langerhans cell histiocytosis: recommendations from an expert panel on behalf of Euro-Histio-Net

Recommendation

Grade

Full Blood Count (Hemoglobin, White blood cell and differential count, Platelet count)

D2

Blood Chemistry (Total protein, Albumin, Bilirubin , ALT (SGPT), AST (SGOT)

D2

Alkaline phosphatase (AP), gammaglutamyl transpeptidase (γGT)

 

Creatinine, Electrolytes, CRP (C-reactive Protein)

 

Erythrocyte Sedimentation Rate (ESR)

D1

Coagulation Studies (INR/PT, Fibrinogen)

D2

Thyroid Stimulating Hormone (TSH), freeT4

D2

Morning Urine Osmolarity

D1

Urine Test Strip

D2

Ultrasound (liver, spleen, lymph-nodes, thyroid gland)

D2

Chest Radiograph (CXR)

D2

Low Dose Whole Body (Bone) CT (if not available: X-Ray Skeletal/Scull Survey)

D2

Optional: Baseline Head-MRI

D2

Optional: PET-CT instead of Ultrasound, CXR and Bone CT

D2