Figure 4
From: Natural history of Barth syndrome: a national cohort study of 22 patients
Overall survival and survival according to birth year of the French Barth syndrome cohort. A) Kaplan-Meier plot and 95% confidence intervals showing the overall survival of the French Barth syndrome cohort. Time is expressed in years since birth. B) Kaplan-Meier plot showing the survival of the French Barth syndrome cohort according to birth year (before and in or after 2000). Even though the total number of patients is quite limited, the difference in survival is both important (survival at 5 years: 22% for patients born before 2000 and 70% for patients born in or after 2000) and statistically significant (p = 0.009). This suggests that recent progress in the management of heart dysfunction may improve the survival of patients with BTHS.