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Table 2 Characteristics of the eight patients with sarcoidosis and glomerular disease occurring simultaneously

From: Clinicopathological study of glomerular diseases associated with sarcoidosis: a multicenter study

 

pt1

pt2

pt3

pt4

pt5

pt6

pt7

pt8

pt9

Type of GD

MN

MN

FSGS

FSGS

IgAN

IgAN

IgAN

MCNS

MN

Age at GD diagnosis (years)

51.9

50.6

56.4

46.3

52.5

22.2

25.2

28.7

44

Proteinuria level (g/d)

1.8

4.3

1.7

6.6

1

1.3

1

3

7

GFR (ml/min/1.73 m2)

35

69

56

60

97

96

81

92

89

Serum Albumin (g/L)

43

31.6

38

27

17

35

38

29

16

GTIN (+ present -absent)

+

-

+

-

+

+

-

+

+

Affected organs

Lymph nodes Erythema Nodosum

Spleen Lymph nodes parotitis

Lung Skin

Lung Lymp nodes

Lung Lymph nodes Liver Spleen Bone marrow Salivary glands

Lung Lymph nodes Liver Spleen parotidis

Lymph nodes

Lymph nodes Skin epididymitis

Lymph nodes Salivary glands

Radiographic classification (stage)

1

0

2

2

3

1

1

1

1

Steroid treatment

yes

no

yes

yes

yes

yes

yes

yes

yes

Remission of GD with steroids

CR

no

CR

no

PR

CR

CR

PR

PR

Remission of sarcoidosis with steroids

no

no

no

no

yes

no

yes

yes

yes

Other immunosuppressive treatment (date of introduction)

Plaquenil (M7)

 

Plaquenil (M19)

Aza (M13)

 

Aza (M18)

 

MMF (M12)

 

Duration of follow-up (years)

9

0.6

2.7

5

0.6

3.3

10.8

2

0.6

GFR at the end of follow-up (mL/min/1.73 m2)

56.8

67

died

dialysis

86.6

120.4

78.1

80

72

  1. GD: Glomerular disease, MN: membranous nephropathy, IgAN: IgA nephropathy, MCNS: minimal change nephrotic syndrome, FSGS: focal and segmental glomerulosclerosis, GTIN: granulomatous tubulointerstitial nephritis, GFR: glomerular filtration rate, Aza: azathioprine, MMF: Mycophenolate Mofetil, CR: complete remission, PR: partial remission.