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Table 4 Multiple logistic regression analysis for the development of a first complication in patients in the ERT and NH cohort and the development of a second complication in patients with a previous complication

From: Long term enzyme replacement therapy for Fabry disease: effectiveness on kidney, heart and brain

 

First complication

Second complication

 

Odds ratio (95% CI)1

p-value

Odds ratio (95% CI)2

p-value

Age in years

1.05 (1.0-1.1)

0.012

1.02 (0.93-1.1)

0.75

Gender (male)

4.45 (1.6-12.1)

0.003

2.8 (0.40-19.6)

0.30

ERT duration in years

0.81 (0.68-0.96)

0.015

0.52 (0.31-0.88)

0.014

  1. The odds ratio represents the additional risk of developing a complication based on age, gender and ERT treatment.
  2. 1Intercept = e-3.024; 2Intercept = e-0.326.