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Table 4 Multiple logistic regression analysis for the development of a first complication in patients in the ERT and NH cohort and the development of a second complication in patients with a previous complication

From: Long term enzyme replacement therapy for Fabry disease: effectiveness on kidney, heart and brain

  First complication Second complication
  Odds ratio (95% CI)1 p-value Odds ratio (95% CI)2 p-value
Age in years 1.05 (1.0-1.1) 0.012 1.02 (0.93-1.1) 0.75
Gender (male) 4.45 (1.6-12.1) 0.003 2.8 (0.40-19.6) 0.30
ERT duration in years 0.81 (0.68-0.96) 0.015 0.52 (0.31-0.88) 0.014
  1. The odds ratio represents the additional risk of developing a complication based on age, gender and ERT treatment.
  2. 1Intercept = e-3.024; 2Intercept = e-0.326.