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Table 4 Summary of adverse drug reactions

From: Phase I/II clinical trial of enzyme replacement therapy with idursulfase beta in patients with mucopolysaccharidosis II (Hunter Syndrome)

Group

Number of subjects with events

Number of events

Events

Comparator 0.5 mg/kg/week (N = 11)

2

19

Urticaria (13)

Rash (4)

Itching (1)

Wheezing (1)

Idursulfase beta 0.5 mg/kg/week (N = 10)

1

4

Urticaria (3)

Itching (1)

Idursulfase beta 1.0 mg/kg/week (N = 10)

2

3

Urticaria (3)