Table 4 Comparison of published cohorts
From: Assessment and management of pulmonary alveolar proteinosis in a reference center
Seymour (2002)[8] (n = 410) | Inoue (2008)[10] (n = 248) | Xu (2009)[11] (n = 241) | Bonella (2010)[12] (n = 70) | Campo (2012) [this paper] (n = 81) | |
|---|---|---|---|---|---|
Age at Diagnose (mean, range) | 39 (30-46) | 51 (41-58) | 42 (n.a) | 43 (18-78) | 40 (26-54) |
Ratio Male/Female | 2.6 | 2.0 | 2.2 | 1.3 | 2.0 |
Primary PAP (%) | n.a. | 90 | n.a. | 91 | 90 |
Secondary PAP (%) | n.a. | 10 | n.a. | 9 | 3.7 |
Time to diagnosis (months) | 7 (3-19) | 10 (4-36) | n.a. | 9 (1-36) | 11 (0-27) |
Spontaneous remitters (%) | 6 | 5 | n.a. | 5 | 7 |
Smoking habits (%) | |||||
Never | 28 | 43 | - | 21 | 36 |
Previous | n.a. | 29 | - | 30 | 42 |
Current | n.a. | 29 | - | 49 | 22 |
Dust exposure (%) | n.a. | 26 | n.a. | 54 | 32 |
Whole lung lavage | 54% | n.a. | 59% | 90% | 54% |