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Table 4 Comparison of published cohorts

From: Assessment and management of pulmonary alveolar proteinosis in a reference center

  Seymour (2002)[8] (n = 410) Inoue (2008)[10] (n = 248) Xu (2009)[11] (n = 241) Bonella (2010)[12] (n = 70) Campo (2012) [this paper] (n = 81)
Age at Diagnose (mean, range) 39 (30-46) 51 (41-58) 42 (n.a) 43 (18-78) 40 (26-54)
Ratio Male/Female 2.6 2.0 2.2 1.3 2.0
Primary PAP (%) n.a. 90 n.a. 91 90
Secondary PAP (%) n.a. 10 n.a. 9 3.7
Time to diagnosis (months) 7 (3-19) 10 (4-36) n.a. 9 (1-36) 11 (0-27)
Spontaneous remitters (%) 6 5 n.a. 5 7
Smoking habits (%)      
Never 28 43 - 21 36
Previous n.a. 29 - 30 42
Current n.a. 29 - 49 22
Dust exposure (%) n.a. 26 n.a. 54 32
Whole lung lavage 54% n.a. 59% 90% 54%