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Table 3 Analysis of baseline pulmonary function data between PAP patients never lavaged and lavaged once or more times

From: Assessment and management of pulmonary alveolar proteinosis in a reference center

   No WLL (n = 19) 1 WLL (n = 18) >1 WLL (n = 10) p value
CEA median (iqr) 5 (3-8) 13 (8-30) 8.5 (7-12) 0.0418019 1
Cyfra median (iqr) 4.5 (2-5) 13 (9-16) 5 (2-32.5) 0.0275304 2
LDH mean (sd) 368.67 (109.78) 622.14 (263.26) 536.2 (166.89) 0.0126793 3
NSE mean (sd) 19.2 (5.72) 20.6 (6.22) 22 (4) 0.8022085
DSS mean (sd) 2.67 (1.22) 3.06 (1.25) 3.57 (.98) 0.3353056
FEV1 (%Pred) mean (sd) 82.82 (14.79) 75.8 (22.63) 65.88 (12.23) 0.1087558
FEV1/Vc (%Pred) mean (sd) 100.43 (5.17) 105.47 (8.71) 103 (8.25) 0.1804334
FVC (%Pred) mean (sd) 83.89 (13.16) 73.17 (21.83) 61.57 (9.03) 0.0145088 4
PaCo2 (mmHg) mean (sd) 35.15 (3.4) 33.91 (3.9) 33.93 (4.07) 0.6664365
PaO2 (mmHg) mean (sd) 70.95 (13.25) 62.64 (13.01) 59.2 (8.96) 0.1019723
TLC (%pred) mean (sd) 79.43 (8.15) 74.47 (17.92) 65.43 (14.03) 0.115102
DLco (%pred) mean (sd) 61.89 (19.27) 45.95 (14.29) 42.63 (11.17) 0.0038198 5
DLco (mmolkpas) mean (sd) 6.52 (3.41) 4.08 (1.61) 3.84 (1.06) 0.0087515 6
ΔA-aO2 mean (sd) 34.85 (16.28) 44.84 (16.43) 48.14 (8.76) 0.1299473
  1. 1no WLl vs 1 WLL: p = 0.006057; 2no WLl vs 1 WLL: p = 0.005202; 3no WLl vs 1 WLL: p = 0.011; 4no WLl vs >1 WLL: p = 0.016; 5no WLl vs 1 WLL: p = 0.010, no WLl vs >1 WLL: p = 0.021; 6no WLl vs 1 WLL: p = 0.015, no WLl vs >1 WLL: p = 0.05.