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Table 3 Analysis of baseline pulmonary function data between PAP patients never lavaged and lavaged once or more times

From: Assessment and management of pulmonary alveolar proteinosis in a reference center

  

No WLL (n = 19)

1 WLL (n = 18)

>1 WLL (n = 10)

p value

CEA

median (iqr)

5 (3-8)

13 (8-30)

8.5 (7-12)

0.0418019 1

Cyfra

median (iqr)

4.5 (2-5)

13 (9-16)

5 (2-32.5)

0.0275304 2

LDH

mean (sd)

368.67 (109.78)

622.14 (263.26)

536.2 (166.89)

0.0126793 3

NSE

mean (sd)

19.2 (5.72)

20.6 (6.22)

22 (4)

0.8022085

DSS

mean (sd)

2.67 (1.22)

3.06 (1.25)

3.57 (.98)

0.3353056

FEV1 (%Pred)

mean (sd)

82.82 (14.79)

75.8 (22.63)

65.88 (12.23)

0.1087558

FEV1/Vc (%Pred)

mean (sd)

100.43 (5.17)

105.47 (8.71)

103 (8.25)

0.1804334

FVC (%Pred)

mean (sd)

83.89 (13.16)

73.17 (21.83)

61.57 (9.03)

0.0145088 4

PaCo2 (mmHg)

mean (sd)

35.15 (3.4)

33.91 (3.9)

33.93 (4.07)

0.6664365

PaO2 (mmHg)

mean (sd)

70.95 (13.25)

62.64 (13.01)

59.2 (8.96)

0.1019723

TLC (%pred)

mean (sd)

79.43 (8.15)

74.47 (17.92)

65.43 (14.03)

0.115102

DLco (%pred)

mean (sd)

61.89 (19.27)

45.95 (14.29)

42.63 (11.17)

0.0038198 5

DLco (mmolkpas)

mean (sd)

6.52 (3.41)

4.08 (1.61)

3.84 (1.06)

0.0087515 6

ΔA-aO2

mean (sd)

34.85 (16.28)

44.84 (16.43)

48.14 (8.76)

0.1299473

  1. 1no WLl vs 1 WLL: p = 0.006057; 2no WLl vs 1 WLL: p = 0.005202; 3no WLl vs 1 WLL: p = 0.011; 4no WLl vs >1 WLL: p = 0.016; 5no WLl vs 1 WLL: p = 0.010, no WLl vs >1 WLL: p = 0.021; 6no WLl vs 1 WLL: p = 0.015, no WLl vs >1 WLL: p = 0.05.