Skip to main content

Table 1 Demographics of the 81 subjects with surfactant associated disorders

From: Assessment and management of pulmonary alveolar proteinosis in a reference center

  n. %
Classification   
Primary PAP   
Idiopathic + autoimmune1 73 90
Hereditary2 1 1
Secondary PAP3 3 4
PAP-like4 4 5
Gender   
Male 54 66.5
Female 27 33.5
Smoking status   
Current 18 22
Former 34 42
Never 29 36
  1. 1 We began to measure serum GMAb level in 2004, thus for accuracy in this group we included patients with idiopathic PAP (n = 42, those diagnosed before 2004) and patients with autoimmune PAP (n = 31, those diagnosed after 2004), although currently they are considered synonymous. 2 This subject was affected by PAP due to a GM-CSF receptor αchain mutation[17]. 3 This group includes two subjects with PAP secondary to hematologic disorders (1 chronic myeloid leukemia and 1 myelodysplastic syndrome) and 1 subject affected by lysinuric protein intolerance (the latter’s case history has already been reported)[18, 19]. 4 This group includes four subjects with a mutation in the ABCA3 gene (manuscript in preparation).