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Table 3 The main findings of genetically analyzed IP patients and CNS anomalies according to the presence of genetically confirmed IKBKG mutation for the period 2001-2012

From: Systematic review of central nervous system anomalies in incontinentia pigmenti

IP patients with and without genetical confirmation of the IKBKG mutation Number of Distribution of CNS anomaly types in numbers Distribution of IP patients according to severity of anomalies in numbers
  Neurologically investigated IP patients with CNS anomalies CNS anomaly types CNS anomaly types per patient Seizures Mental retardation Motor impairment Microcephaly CNS anomalies found in small number or unspecified IP patients with mild CNS anomalies IP patients with severe CNS anomalies
Total 205 329 1.60 141 66 82 12 28 80 125
IP patients without genetical confirmation 155 252 1.62 111 55 69 9 8 57 98
IP patients with genetical confirmation 50 77 1.54 30 11 13 3 20 23 27