|
Number of
|
Distribution of CNS anomaly types in numbers **
|
Number of
|
---|
Sex
|
IP patients
|
Neurologically investigated IP patients
|
Neurologically investigated IP patients with CNS anomalies
|
CNS anomalies
|
CNS anomaly types per patient
|
Seizures
|
Mental retardation
|
Motor impairment
|
Microcephaly
|
CNS ** anomalies found in small number or unspecified
|
Neurologically investigated IP patients with mild CNS anomalies
|
Neurologically investigated IP patients with severe CNS anomalies
|
---|
Total*
|
1,393
|
795
|
242
|
393
|
1.62
|
165
|
80
|
101
|
16
|
31
|
92
|
150
|
Female
|
1,295
|
719
|
221
|
361
|
1.63
|
152
|
73
|
94
|
15
|
27
|
84
|
137
|
Male
|
92
|
76
|
21
|
32
|
1.52
|
13
|
7
|
7
|
1
|
4
|
8
|
13
|
- * For six patients, data concerning sex were not available in the literature.
- ** The task of counting and identifying anomalies in some references was challenging because there were only lists of observed anomalies with no exact numbers. These lists included frequent types of CNS anomalies such as seizures, motor impairment, mental retardation, and microcephaly. These anomalies were classified as unspecified anomalies together with different anomalies presented in small numbers. In this investigation, of 31 registered rare or unspecified CNS anomalies, 15 were unspecified but frequent types of CNS anomalies (seizures, motor impairment, mental retardation, and microcephaly). Because of these difficulties, the exact number of frequent types of CNS anomalies such as seizures, motor impairment, mental retardation, and microcephaly was actually higher than those presented in the tables.