Specific cancer rates may differ in patients with hereditary haemorrhagic telangiectasia compared to controls

Table 4 Crude and age adjusted HHT odds ratios for the four most common cancers

	Crude odds ratio (95% CI)	p value	Age adjusted odds ratio (95% CI)	p value
All cancers	0.83 (0.72, 0.96)	0.012	1.04 ( 0.90, 1.21)	0.53
Prostate	1.11 (0.71, 1.76)	0.64	1.37 (0.87, 2.19)	0.18
Colorectal	1.04 (0.65, 1.65)	0.89	1.30 (0.81, 2.08)	0.28
Breast	1.18 (0.84, 1.65)	0.35	1.52 (1.07, 2.14)	0.018
Lung	0.38 (0.24, 0.60)	<0.0001	0.48 (0.30, 0.77)	0.0023

Logistic regression was performed in all HHT patients and controls for all cancers, colorectal and lung cancers, in males only for prostate cancer, and in females only for breast cancer. The age adjusted p values for contribution of HHT status were calculated post estimation using Wald test.

ISSN: 1750-1172