From: Phenotypic variability and identification of novel YARS2 mutations in YARS2 mitochondrial myopathy, lactic acidosis and sideroblastic anaemia
YARS2 Variant
K m (Ī¼M)
kcat(min-1)
kcat/K m (Efficiency)
Loss of Efficiencya(Fold change)
WT
1
34
p.Gly191Asp
0.9
38