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Table 1 Cell lines used in this study

From: Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation

Name

Origin

Human dermal fibroblasts

HDF-WTa

Skin

HDF-WTb

Skin

FF-WT-BJ

Foreskin (Stemgent 08–0027)

HDF-WT-1323

Fibroblast (Cell Applications, 1323)

HDF-WT-1388

Fibroblast (Cell Applications, 1388)

HDF-WT-TIG120

Collection of Research Bioresources, Japan

HDF-FOP1

Skin Fibroblast, Corielle GM00513

HDF-FOP2

Skin Fibroblast, Corielle GM00783

HDF-FOP3

Skin

HDF-FOP4

Skin

HDF-FOP5

Skin

Control retroviral iPS cell lines (wildtype ACVR1)*

vWTa

HDF

vWTb

HDF

vWT-TIG120-4f1

HDF

vWT-201B2

HDF

vWT-201B7

HDF

FOP retroviral iPS cell lines (ACVR1 R206H)*

vFOP1-1

HDF-FOP1

vFOP1-4

HDF-FOP1

vFOP2-1

HDF-FOP2

vFOP2-2

HDF-FOP2

vFOP4-1

HDF-FOP4

vFOP4-3

HDF-FOP4

vFOP5-22

HDF-FOP5

Control episomal iPS cell lines (Wildtype ACVR1)**

eWT-1323-2

HDF-1323

eWT-1323-4

HDF-1323

eWT-BJ2

FF-BJ

eWT-BJ4

FF-BJ

FOP episomal iPS cell lines (ACVR1 R206H)**

eFOP1-1

HDF-FOP1

eFOP1-10

HDF-FOP1

eFOP2-3

HDF-FOP2

eFOP2-8

HDF-FOP2

eFOP3-2

HDF-FOP3

eFOP3-4

HDF-FOP3

  1. Summary of the FOP and control human dermal fibroblasts and iPS cell lines used in this study, including naming, classification (control vs. FOP), and original tissue source. HDF, human dermal fibroblast; FF, foreskin fibroblast. Please see Additional file 1: Table S1 for a detailed summary of the iPS cell characterization. Method of making iPS cells: *, Retroviral OSKM ; **, Epi(Y4).