Figure 7From: Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formationHuman iPS cells for disease modeling. Our results suggest an increased disposition towards mineralization and chondrogenesis, consistent with modeling the early developmental and heterotopic bone formation processes. Our in vitro model will allow detailed interrogation of the mechanisms regulating bone formation and triggers of FOP flares, potentially identifying novel treatments for treating pathologic bone diseases.Back to article page