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Table 7 Details of patients divided according to syndromic vs non-syndromic features

From: A prospective observational study of associated anomalies in Hirschsprung’s disease

 

Syndromic, n (%, 95%CI)

Non-syndromic, n (%, 95% CI)

p

Patients, n

10 (9%, 5%-16%)

96 (91%, 83%-95%)

 

Median age

2,25

2,42

n.a.

Male to female ratio

2,33:1

3,57:1

0,6912

S-HSCR

6 (60%, 31%-83%)

73 (76%, 67%-83%)

0,2719

Other HSCR forms

4 (40%, 17%-69%)

23 (24%, 16%-33%)

VI

6 (60%, 31%-83%)

40 (41,7)

0,7918

CAKUT

4 (40%, 17%-69%)

18 (18,7)

0,2106

CHD

5 (50%, 24%-76%)

0 (0%, 0%-5%)

0,0001

HI

1 (10%, 18%-40%)

4 (4%, 2%-10%)

0,3968

CNS anomalies

0 (0%, 0%-33%)

1 (1%, 0,2%-57%)

1,000

OTHER

3 (30%, 11%-60%)

10 (10%, 6%-18%)

0,1044

  1. Legend: n.a., Not assessed.
  2. Although associated anomalies were encountered more frequently in syndromic patients, only CHD showed a statistically significant association.