Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study

Table 3 Change in the SARA Total Score, functional stage, EQ-5D and SCAFI-AB from baseline to six-month visit

Global patient impression	SARA Total Score			Functional stage			EQ-5D			SCAFI-AB
	N	Mean	STD	N	Mean	STD	N	Mean	STD	N	Mean	STD
Stable	83	0.06	2.61	86	0.02	0.45	85	2.52	20.88	73	−0.02	0.39
Worse	132	0.95	2.64	132	0.21	0.51	129	−3.30	23.02	112	−0.09	0.34
Better	7	−0.86	2.06	7	−0.14	0.24	6	−3.50	18.43	6	0.18	0.48
All	222	0.56	2.65	225	0.13	0.49	220	−1.05	22.20	191	−0.06	0.36
Global physician impression	SARA Total Score			Functional stage			EQ-5D			SCAFI-AB
	N	Mean	STD	N	Mean	STD	N	Mean	STD	N	Mean	STD
Stable	103	0.18	2.33	108	0.04	0.46	105	−1.46	20.19	95	0.01	0.30
Worse	106	1.18	2.58	105	0.22	0.50	100	−2.13	23.68	88	−0.14	0.42
Better	14	−1.63	2.89	14	0.07	0.47	14	12.29	22.38	9	−0.06	0.33
All	223	0.54	2.58	227	0.13	0.49	219	−0.89	22.16	192	−0.06	0.37

Larger numbers reflect worse disease severity in the SARA Total Score and Functional Stage while the reverse applies to EQ-5D and SCAFI-AB.

ISSN: 1750-1172