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Table 3 Change in the SARA Total Score, functional stage, EQ-5D and SCAFI-AB from baseline to six-month visit

From: Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study

Global patient impression SARA Total Score Functional stage EQ-5D SCAFI-AB
  N Mean STD N Mean STD N Mean STD N Mean STD
Stable 83 0.06 2.61 86 0.02 0.45 85 2.52 20.88 73 −0.02 0.39
Worse 132 0.95 2.64 132 0.21 0.51 129 −3.30 23.02 112 −0.09 0.34
Better 7 −0.86 2.06 7 −0.14 0.24 6 −3.50 18.43 6 0.18 0.48
All 222 0.56 2.65 225 0.13 0.49 220 −1.05 22.20 191 −0.06 0.36
Global physician impression SARA Total Score Functional stage EQ-5D SCAFI-AB
  N Mean STD N Mean STD N Mean STD N Mean STD
Stable 103 0.18 2.33 108 0.04 0.46 105 −1.46 20.19 95 0.01 0.30
Worse 106 1.18 2.58 105 0.22 0.50 100 −2.13 23.68 88 −0.14 0.42
Better 14 −1.63 2.89 14 0.07 0.47 14 12.29 22.38 9 −0.06 0.33
All 223 0.54 2.58 227 0.13 0.49 219 −0.89 22.16 192 −0.06 0.37
  1. Larger numbers reflect worse disease severity in the SARA Total Score and Functional Stage while the reverse applies to EQ-5D and SCAFI-AB.