Skip to main content

Table 6 Recommendations for monitoring iron overload

From: Organizing national responses for rare blood disorders: the Italian experience with sickle cell disease in childhood

Recommendations

Evidence

Serum ferritin level could increase during VOC; assessment at steady state is recommended.

C

Serial measurements of serum ferritin and iron intake are recommended before starting iron chelation therapy.

C

LIC (liver iron concentration), measured by magnetic resonance T2* or R2*, SQUID (superconducting quantum interference device), or MID (magnetic iron detector), all techniques available in Italy, should be assessed before starting iron chelation therapy.

C

Cardiac iron assessment, measured by magnetic resonance T2*, is recommended before starting iron chelation therapy.

C

Back to article page

Orphanet Journal of Rare Diseases

ISSN: 1750-1172