Figure 1From: Niemann-Pick disease type C symptomatology: an expert-based clinical descriptionClinical assessment of vertical supranuclear gaze palsy. During the neurological evaluation of eye movements, assessing eye pursuit movements alone (left) is insufficient: voluntary saccades must be tested (right). The examiner should require the subject to visually fixate on two separate objects, e.g. the examiner’s finger and a hatpin, which are displaced first horizontally and then vertically (up and down), but always within the subject’s visual field. The subject is then asked to look at each object alternately.Back to article page