Figure 3

Correlation of central and peripheral motor damage. (A and B) Nerve conduction velocity (NCV) and F wave latency of the ulnar nerve correlated with central motor conduction time (CMCT) to the abductor digiti minimi muscle (ADM) (r = 0.249; p < 0.004 and r = −0.280; p < 0.002, respectively). (C and D) Accordingly, NCV and F wave latency of tibial the nerve correlated with CMCT to abductor hallucis muscle (AH) (r = 0.463; p < 0.0001 and r = −0.270; p < 0.09, respectively). Patients with SPG4 mutations are indicated by red triangles, other patients by black squares.