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Figure 5 | Orphanet Journal of Rare Diseases

Figure 5

From: Identification and characterization of regulatory elements in the promoter of ACVR1, the gene mutated in Fibrodysplasia Ossificans Progressiva

Figure 5

Identification of the basal promoter. Deletion constructs Pr-0.3, Pr-0.16, Pr-0.072 schematically represented in Figure 3A were transiently transfected into U2OS (A), HeLa (B), C2C12 (C), ATDC5 (D) to characterize the basal promoter region. Results are expressed as relative to the activity of the pGL3-Promoter vector carrying the SV40 promoter region (PV, 100%). The data represent the mean ± SD (error bars) of independent experiments (3 ≥ n ≥ 5) carried out in triplicate with p < 0.05*, p < 0.01**, or p < 0.001***. comparing the activity of each deletion construct with that of the SV40 promoter (PV).

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172