|
Total
|
35
|
|---|
|
Male/female
|
9/26
|
|
Age (years)
|
56.1±9.8
|
|
Adrenalectomy
|
22 (63%)
|
|
Hypercortisolism
| |
|
- SCS
|
13 (37%)
|
|
- CCS
|
22 (63%)
|
|
Diameter adrenal (mm)
| |
|
- left SCS
|
31.7±10.1
|
|
- left CCS
|
46.1±16.9*
|
|
- right SCS
|
27.2±8.8
|
|
- right CCS
|
43.6±17.0*
|
|
Hypertension
| |
|
- SCS
|
7 (54%)
|
|
- CCS
|
17 (77%)
|
|
Diabetes mellitus
| |
|
- SCS
|
6 (46%)
|
|
- CCS
|
6 (29%)
|
|
Bone loss
| |
|
- Osteopenia
| |
|
• SCS
|
4 (31%)
|
|
• CCS
|
4 (18%)
|
|
- Osteoporosis
| |
|
• SCS
|
5 (42%)
|
|
• CCS
|
5 (24%)
|
|
Midnight cortisol (nmol/l)
| |
|
- SCS
|
184±80
|
|
- CCS
|
319±145*
|
|
Urinary free cortisol (nmol/24h)
| |
|
- SCS
|
481±121 (0% > URL)
|
|
- CCS
|
1048±197* (37% > URL)
|
|
Cortisol after dexamethasone (nmol/l)
| |
|
- SCS
|
145±131 (92% > URL)
|
|
- CCS
|
296±183* (95% > URL)
|
|
ACTH (pmol/l)
| |
|
- SCS
|
1.47±0.92 (39% nd)
|
|
- CCS
|
0.85±0.89 (85% nd)
|
- SCS: subclinical Cushing’s syndrome, CCS: clinical Cushing’s syndrome, URL: upper reference limit, nd: non-detectable, data presented as mean±SD, *P<0.05, compared to SCS. ¶ ACTH levels below the lower detection limit of 1.10 pmol/l were set at 0.55 pmol/l.
