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Table 2 Comorbidities and pathologic serologic parameters in 259 patients with PG

From: Associated factors and comorbidities in patients with pyoderma gangrenosum in Germany: a retrospective multicentric analysis in 259 patients

  Patients (absolute) Patients (relative in%)
Gastrointestinal diseases 66 22.5 (overall)
Chronic active hepatitis 11 16.7
Ulcerative colitis 17 25.8
Crohn’s disease 7 10.6
Diverticulosis 9 13.6
Gastric disorders 13 19.7
Gastric/duodenal ulcer 4 6.0
Gastrointestinal polyps 2 3.0
Steatohepatitis 1 1.5
Others 2 3.0
Arthropathy 48 18.5 (overall)
Rheumatoid arthritis 24 50.0
a) seropositive 21 43.8
b) seronegative 3 6.3
Arthrosis 17 25.8
Ankylosing spondylitis 2 4.1
Psoriasis arthropathy 3 6.3
Osteoporosis 2 4.1
Haematological diseases 10 3.9 (overall)
Leukemia 3 30.0
a) AML 1 10.0
b) CML 2 20.0
Lymphoma (T-cell) 2 20.0
Multiple myeloma 2 20.0
Macroglobulinemia 3 30.0
Neoplasia 22 8.5 (overall)
Breast cancer 6 27.3
Lung cancer 3 13.6
Prostate cancer 3 13.6
Malignant melanoma 3 13.6
Hepatocellular carcinoma 2 9.1
Ovarian cancer 2 9.1
Colorectal cancer 1 4.5
Laryngeal cancer 1 4.5
Glioblastoma 1 4.5
Endocrine disorders 95 36.7 (overall)
Diabetes mellitus 66 69.5
a) type II 60 63.2
b) type I 6 6.3
Thyroid disease 29 30.5
Hyperthyroidism 9 9.5
Hypothyroidism 18 19.0
Hashimoto’s thyroiditis 2 2.1
Serological parameters 181 69.9 (overall)
Anemia 118 65.2
Microcytic anaemia 28 15.5
Auto-antibodies 45 24.9
Anti-nuclear antibodies 30 16.6
C-reactive protein 181 100
Leukocytosis 117 64.6
Elevated creatinine 52 28.7
Renal failure 11 6.1